I have a 2004 Gallardo (E -gear). The only problem I have ever had was the clutch. Once the later style clutch was fitted, the car has been faultless ever since. I put an after market sports exhaust on it (Tubi) and now it sounds great.
What might attract me to a later version though, is the changed gear box ratios. Not sure what year the change in ratios took place, but first gear on early Gallardos is really high, no doubt contributing to the early clutch failures. I would imagine that later model cars with the revised gear ratios would have better take-off from a standing start, with less stress and wear on the clutch. But on the other side of the coin, the higher ratio first gear is high enough to be a really useful and useable feature for tight twisty fun roads - I often drop back to first gear in corners, and boy do you accelerate fast out of those turns in first
Also, being able to raise the nose to go over kerbs etc would be handy. This feature is not on my 2004 car.